Complement resistance is a virulence factor of Branhamella (Moraxella) catarrhalis
نویسندگان
چکیده
منابع مشابه
Moraxella (Branhamella) catarrhalis bacteremia in an immunocompetent children
Moraxella catarrhalis is an aerobic, Gram-negative diplococcus that commonly inhabits the upper respiratory tract (1). M. catarrhalis is now considered as an important cause of respiratory tract infections in children and adults with chronic obstructive pulmonary disease (COPD) (2, 3, 4). M. catarrhalis is now considered a common cause of otitis media in children and sinusitis in both children ...
متن کاملBranhamella catarrhalis
A modified oxidation-fermentation medium was developed as a practical medium for highly sensitive and specific detection of acid production from carbohydrates by Neisseria spp. and Branhamella catarrhalis. A total of 756 strains representing 17 Neisseria spp. and Branhamella catarrhalis were tested in this medium, in which the protein concentration was reduced relative to the carbohydrate conce...
متن کاملPurification and characterization of a high-molecular-weight outer membrane protein of Moraxella (Branhamella) catarrhalis.
Moraxella (Branhamella) catarrhalis is an important bacterial cause of otitis media in children and lower respiratory tract infections in adults. In this study, we describe the presence of a novel high-molecular-weight outer membrane protein (HMW-OMP). This protein varies from 350 to 720 kDa in apparent molecular mass among strains by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (S...
متن کاملMoraxella (Branhamella) catarrhalis--clinical and molecular aspects of a rediscovered pathogen.
Since its discovery at the end of the nineteenth century, Moraxella (Branhamella) catarrhalis has undergone several changes of nomenclature and periodic changes in its perceived status as either a commensal or a pathogen. Molecular analysis based on DNA hybridisation or 16S rDNA sequence comparisons has established its phylogenetic position as a member of the Moraxellaceae and shown that it is ...
متن کاملPhage antibodies obtained by competitive selection on complement-resistant Moraxella (Branhamella) catarrhalis recognize the high-molecular-weight outer membrane protein.
We used competitive panning to select a panel of 10 different human antibodies from a large semisynthetic phage display library that distinguish between serum complement-resistant and complement-sensitive strains of the gram-negative diplococcus Moraxella (Branhamella) catarrhalis. Western blotting analyses and inhibition enzyme-linked immunosorbent assays showed that all phage antibodies were ...
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ژورنال
عنوان ژورنال: FEMS Immunology and Medical Microbiology
سال: 1995
ISSN: 0928-8244
DOI: 10.1016/0928-8244(95)00026-4